The proven health benefits of sophora flavescens extract will leave you with a smile. antioxidants, skin conditioning: Recommendation for sophora flavescens root extract usage levels up to: not for fragrance use. It grows in a tropical climate. Oxymatrine has been proven to be an effective antibacterial agent that promotes hair growth and circulation. If you want to buy Oxymatrine, please contact us in following way.  |  97 ($7.49/Fl Oz) Of all the different sophora species and plant parts used in Chinese medicine, Sophora flavescens roots are by far the most frequently used, which is why the common name “sophora” is appropriately selected to represent it. Introduction: Sophora root extract is an extract of leguminous plant Sophora flavescens, whose main active ingredient is oxymatrine content of … HPLC-based activity profiling of extracts the traditional Chinese herbal drug Kushen (Sophora flavescens root) led to the identification of the 8-lavandulyl flavonoids, kushenol I, sophoraflavanone G, and (−)-kurarinone, and the related chalcone kuraridine as GABA A receptor modulators (Yang, Baburin, Plitzko, Hering, & Hamburger, 2011). Oxymatrine. Oxymatrine, as sophora angustifolia root extract, provides rich nutrition for hair and scalp. In addition, a clinical trial of a cream containing 0.05% S. flavescens extract on human skin showed it had a significant effect on skin whitening by mechanical and visual evaluation (1.14-fold). Objective: Matrine and oxymatrine have similar physiological activities, but there are still differences. And now it is consumed in various forms, like sophora flavescens supplement, extract… To elucidate the mechanism of action of S. flavescens extract, we used DNA microarray technology. Epub 2013 Feb 22. Sophora Flavescens is a shrub. Sophora Tincture Alcohol Extract, Organic Ku Shen, Sophora (Sophora Flavescens) Dried Root Tincture Supplement (4 FL OZ) 5.0 out of 5 stars 2 $29.97 $ 29 . From these results, we suggest that naturally occurring S. flavescens extract might be useful as a new whitening agent in cosmetics. As alkaloids, oxymatrine and matrine have same pharmacological effect. Oxymatrine has lower cytotoxicity than retinol; and it exhibits an inhibitory effect on collagenase activity and a promotion of collagen biosynthesis. Oxymatrine has broad-spectrum antibacterial property. Plamed Oxymatrine is white color, high content, and low cost. 2011 Jun;33(3):210-21. doi: 10.1111/j.1468-2494.2010.00616.x. Sophora extract has been used for acne to control bacteria and reduce 5 alpha reductase activity, which synthesizes DHT. sophora flavescens root extract manufacturer/supplier, China sophora flavescens root extract manufacturer & factory list, find qualified Chinese sophora flavescens root extract manufacturers, suppliers, factories, exporters & wholesalers quickly on Made-in-China.com. COVID-19 is an emerging, rapidly evolving situation. Oxymatrine has been widely used in cosmetics, such as Shiseido Elixir Superieur Lifting Moisture Lotion II, Cle De Peau Beaute Gentle Cleansing Foam and other skin care products. In TCM : Sophora Flavescens Root : Ku Shen Jian Meridians associated : Heart, Urinary Bladder, Liver, Small Intestine and Large Intestine. And it is usually used raw. Email: sale@plamed.cn USA.gov. The root known as “Ku Shen” which means “bitter root” in Chinese, has been used in Traditional Medicine for two thousand years to treat a variety of conditions, including diarrhea, jaundice, skin rashes, and to kill parasites. 2016 Apr;68(4):503-13. doi: 10.1111/jphp.12524. by Subhuti Dharmananda, Ph.D., Director, Institute for Traditional Medicine, Portland, Oregon. 2. This post is a little more general, as I have done extensive posts on some specific alkaloids of Kushen (see below). January 16, 2019Cosmetic ingredients. The content of oxymatrine in Kushen root is much higher than that of matrine. Context: And it has a few other names, including Sophora Flavescens radix, light yellow sophora root, Flavescent Sophora Root, Root of Light Yellow Sophora, Sophora Flavescens Root, and more. Sophora root mainly contains alkaloids, flavonoids, quinones, and triterpenoid saponins. What is Sophora Flavescens Extract Matrine Oxymatrine? skin-whitening effect of S. flavescens extract was analyzed on human skin. We conducted a study to determine whether ethanol extract of the roots of S. flavescens has the potential for use as a whitening cosmetic agent by investigating its underlying mechanisms of action. Sophora flavescens Sophora Flavescens (Ku Shen) is a medicinal herb from China that appears to possess mostly anti-cancer properties. Differences Between Oxymatrine and Matrine. Oxymatrine can exert its anti-inflammatory effect through changes of immune cells, cytokines and other inflammatory regulatory factors. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Discussion and conclusion: It has been used to treat a variety of conditions, such as … Tel: +86-29-8821 5350 This study provides important clues toward understanding the effects of S. flavescens extract on the formation and transport of melanosomes. It has a good treatment of eczema and dermatitis, and can alleviate skin itching caused by inflammation. It is extracted from the plant “Sophora Flavescens Ait”, which medicinally mainly refers to the dried root of Sophora Flavescens Ait. 1. 2. Anti-melanogenic effects of Aster spathulifolius extract in UVB-exposed C57BL/6J mice and B16F10 melanoma cells through the regulation of MAPK/ERK and AKT/GSK3β signalling. Draco Natural Products Inc. Test Data Available. The anti-inflammatory mechanism of oxymatrine is due to the stabilization of erythrocyte membrane. China Sophora Flavescens Extract Insecticide Pesticide Matrine, Find details about China Matrine, Oxymatrine from Sophora Flavescens Extract Insecticide Pesticide Matrine - … Ku Shen, also known as Sophora Flavescens, can be used a supplement of a diet that is intended to contribute to the maintenance of healthy skin. Please enable it to take advantage of the complete set of features! not reported and skin conditioning. Results: Plamed Oxymatrine is white color, high content, and low cost. After the digging, for better medicinal quality it should remove the head and small fibrous root, wash clean, and dry immediately or dry after slicing when it is still fresh. Both of them can be transformed in vitro and in vivo; wherein oxymatrine’s nitrogen atom is combined with oxygen by a coordination bond. Combined with other Chinese herb extracts, it has function of anti-inflammatory, blood circulation and cell regeneration. 2013 Apr 19;146(3):824-34. doi: 10.1016/j.jep.2013.02.010. Usui K, Ikeda T, Horibe Y, Nakao M, Hoshino T, Mizushima T. J Dermatol Sci. It has a medicinal history of more than 2,000 years. Int J Cosmet Sci. 2017 Jul 1;25(4):390-395. doi: 10.4062/biomolther.2016.156. Although axonal extension to reconstruct spinal tracts should be effective for restoring function after spinal cord injury (SCI), chondroitin sulfate proteoglycan (CSPG) levels increase at spinal cord lesion sites, and inhibit axonal regrowth. It may also inhibit the 5-Alpha Reductase enzyme and PDE5 potently, promoting hair growth and erectogenesis. (Leguminosae) has been proposed as a new whitening agent for cosmetics, because it has a strong ability to inhibit tyrosinase, a key enzyme in the formation of melanin. Whitening agents act at various levels of melanin production in the skin. Skin conditioning; COSING REF No: 83737 Chem/IUPAC Name: Sophora Flavescens Root Extract is the extract of the roots of Sophora flavescens, Fabaceae 6. 6 Cosmetics Ingredients containing SOPHORA FLAVESCENS ROOT EXTRACT. 2009 Dec 10;10(12):5326-49. doi: 10.3390/ijms10125326. About the Chemical. Materials and methods Materials The ethanol extracts of the roots of S. flavescens and Oxymatrine is commonly known as SOPHORA ANGUSTIFOLIA ROOT EXTRACT in cosmetic formulation. Bitter sophora root, as a medicinal plant, has the functions of clearing heat, diuresis, insecticide, dispelling dampness and so on.It also has the functions of anti-virus, anti-tumor and anti-allergy. Also Oxymatrine acts as an anti-allergic agent; it inhibits physical pain, chemical irritating pain, and neuropathic pain, and relieves skin pain caused by inflammatory allergies. Synonyms. Under certain condition, nitrogen-oxygen bond is cleaved and converted into matrine. Sophora angustifolia root extract is one of the three major plant soothing agents for skin care (the other two are licorice extract and astragalus extract). Clinical medicine. Sophora Angustifolia Root Extract is an extract of the roots of Sophora angustifolia. Materials and methods: SOPHORA ANGUSTIFOLIA EXTRACT, SOPHORA ANGUSTIFOLIA ROOT EXTRACT, and SOPHORA FLAVESCENS ROOT EXTRACT. Tel: 0086-29-88211806 Welcome to click, White Willow Bark (Salix Alba ) Extract for Skin Care, Portulaca Oleracea Extract – Protective Umbrella for Sensitive Skin, Plamed participated in the 2017 Vitafoods Exhibition. After topical application of Sophora flavescens extract onto the back of C57BL/6 mice, the earlier conversion of telogen-to-anagen was induced. Results also showed that key proteins involved in the formation and transport of melanosomes were dramatically downregulated at both mRNA and protein level in keratinocytes exposed to S. flavescens extract. 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